Ianos Adam, Svetlana Sciuca and
Rodica Selevestru
Department
of Pediatrie, State Medical and Pharmaceutical University, Chisinau,
Republic of Moldova
Aim: Identify
associated upper respiratory tract disease in children with solitary
asthma and comorbidity with gastroesophageal reflux disease (GERD)
Methods:
The study included 96 children with solitary asthma (AB) and 98
children with comorbid asthma with GERD aged 5-16 years (p<0.05)
.
Results: The
result of the survey found that most children with comorbid GERD with
AB (87.4±3.29%) were associated with recurrent pharyngitis
in children with group AB solitary in 41,7±4.88% (?2=85.62;
gl=1; p<0.001). Among allergic disorders, which frequently
accompanies AB places allergic rhinitis with a considerable weight in
each batch of children, but with significant prevalence
(p<0.001) in the group of children with AB associated with GERD
56.3±4.91% of cases, and in the group of children with
solitary asthma only 39.8 ± 4.85% cases. The study
identified every 4th child with asthma associated with GERD recurrent
tonsillitis (24.3±4.25%), which is definite statistical
superior compared to children with solitary asthm, where there were 2,5
times fewer cases 9,7±2.93% (?2=24.19; gl=1,
p<0.001). Recurrent laryngitis presence was noticed frequently
in children with comorbid asthma GERD – 12.6±3.29%
cases compared with 5,8±2.32% registered in children with
solitary asthma(?2=8.58; gl=3; p<0.05).
Conclusion:
In the group of children with comorbid asthma GERD with truthfulness
statistics certifies more commonly diseases associated ENT which
confirms the negative role of gastro-esophageal and pharyngeal reflux
in perpetuating the inflammatory process in the upper airway compared
with children with solitary asthma.
Source
: http://erj.ersjournals.com/content/48/suppl_60/PA1252
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