Meriem Mjid1, Hana Blibech1,
Sonia Toujani1, Rihab Bey1, Nozha Ben Salah2, Yassine Ouahchi1, Bechir
Louzir2, Nadia Mhiri1, Jouda Cherif1 and Majed Beji1
1Rabta
Hospital, Respiratory Department, Research Unit 12SP06, Tunis El Manar
University, Faculty of Medicine of Tunis, Tunis, Tunisia, 2Mongi Slim
Hospital, Respiratory Department, Tunis El Manar University, Faculty of
Medicine of Tunis, Tunis, La Marsa Tunisia
Background: Rare
pulmonary tumors have uncommon histology. Overall, these tumors account
for less than 1 % of all lung primary tumors.
Aim: To review clinic-pathologic, radiological and
therapeutic features of these tumors.
Methods: A retrospective analysis was designed in a
pulmonary department in Tunis during 13 years period. Patients with
histological diagnosis of rare primary lung tumor were included. Tumors
were classified according to the World Health Organization
classification of 2014. Staging was made according to 2009 TNM
classification. Clinical, radiological and histo-pathologic data were
analyzed. Metastatic lung tumors were excluded.
Results: Among 1742 patients with a primary lung
malignancy, 10 (6 men, 4 women) patients had a rare lung tumor (0.5%).
The mean age was 59 years [19-82]. The main respiratory symptoms were
hemoptysis, dyspnea and chest pain. CT scan findings consisted of a
huge mass with obstructive pneumonitis in 7cases. Local invasion was
noted in 4cases. Diagnosis was obtained by bronchial biopsy (3cases),
CT guided biopsy (2cases), surgical resection (4cases) and lymph node
biopsy (1case). Histological types were sarcomatoid carcinoma (4cases),
sarcoma (2cases) and carcinoid tumor (4cases). At diagnosis, 5 patients
had a metastatic disease. Pulmonary resection with lymph node
dissection was performed in 4 cases. Chemotherapy was prescribed in 5
patients.Four patients died, the remaining patients are still followed
up.
Conclusion: In addition to a low incidence, rare
pulmonary tumors are usually characterized by the absence of clinical
and radiological updated features which makes their recognition
difficult.Prognosis depends on histological type.
Source
: http://erj.ersjournals.com/content/46/suppl_59/PA4307
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